There is no cure for cri du chat syndrome. Treatment consists of supportive care and developmental therapy.

The extent of mental retardation and other symptoms depends on the size of the chromosomal deletion--larger deletions generally translate into more serious symptoms. With intensive early intervention and special schooling, many cri du chat children can develop adequate social, motor, and language skills. Most individuals with cri du chat syndrome have a normal lifespan.

Based on current knowledge, cri du chat syndrome cannot be prevented